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Because Phil Winslow has a new chance for his work, he decides to move to new neighborhood with his wife, three kids and their beloved Great Dane, Marmaduke. In new place, he must deal with problems which is created by his oversized dog.
Owen Wilson, Emma Stone, George Lopez, Christopher Mintz-Plasse, Steve Coogan, Fergie, Kiefer Sutherland, Damon Wayans Jr., Marlon Wayans, Sam Elliott, Lee Pace, ...